Inflammation is at the heart of many diseases, including spinal osteoarthritis, disc degeneration and much more.
Holistic management of conditions such as spinal degeneration due to osteoarthritis, or degenerative disc disease involves a number of approaches, including the need to manage and hopefully eliminate inflammation.
Unfortunately, low grade inflammation is an increasingly ever present state for many individuals, for a number of reasons, making them susceptible to ongoing issues such as osteoarthritis, as well as other conditions such a heart disease, stroke, cancer and much more.
Whilst anti-inflammatory management for acute spinal conditions, such as the application of ice to an injured area is important, long-term management of chronic low-grade inflammation may well require more involved intervention.
One such intervention is diet.
Certain dietary patterns have been shown to significantly lower the levels of circulating inflammatory chemicals in the body, which is then associated with decreased risk for not only osteoarthritis and disc degeneration, but for many other diseases as well.
Watch the following brief you tube clips, which provide an overview of the role on inflammation in many diseases, as well as the role that certain diets play in sustained inflammation in people
Deopurkar R, Ghanim H, Friedman J, Abuaysheh S, Sia CL, Mohanty P, Viswanathan P, Chaudhuri A, Dandona P. Differential Effects of Cream, Glucose, and Orange Juice on Inflammation, Endotoxin, and the Expression of Toll-Like Receptor-4 and Suppressor of Cytokine Signaling-3. Diabetes Care. 2010 May; 33(5):991-7.
Luoma K, Riihimaki H, Luukkonen R, Raininko R, Viikari-Juntura E, Lamminen A. Low back pain in relation to lumbar disc degeneration. Spine. 2000;25(4):487-92.
Kalichman L, Hunter DJ. The genetics of intervertebral disc degeneration. Associated genes. Joint Bone Spine. 2008;75(4):388-96.
Hangai M, Kaneoka K, Kuno S, Hinotsu S, Sakane M, Mamizuka N, et al. Factors associated with lumbar intervertebral disc degeneration in the elderly. Spine J. 2008;8(5):732-40.
Kauppila LI. Atherosclerosis and disc degeneration/low-back pain–a systematic review. Eur J Vasc Endovasc Surg. 2009;37(6):661-70.
Kauppila LI. Prevalence of stenotic changes in arteries supplying the lumbar spine. A postmortem angiographic study on 140 subjects. Ann Rheum Dis. 1997;56(10):591-5.
Kauppila LI, Mikkonen R, Mankinen P, Pelto-Vasenius K, Maenpaa I. MR aortography and serum cholesterol levels in patients with long-term nonspecific lower back pain. Spine. 2004;29(19):2147-52.
Blekkenhorst LC, Prince RL, Hodgson JM, Lim WH, Zhu K, Devine A, et al. Dietary saturated fat intake and atherosclerotic vascular disease mortality in elderly women: a prospective cohort study. The American journal of clinical nutrition. 2015;101(6):1263-8.
Trumbo PR, Shimakawa T. Tolerable upper intake levels for trans fat, saturated fat, and cholesterol. Nutrition reviews. 2011;69(5):270-8.
Torres N, Guevara-Cruz M, Velazquez-Villegas LA, Tovar AR. Nutrition and Atherosclerosis. Arch Med Res. 2015;46(5):408-26.
Ferdowsian HR, Barnard ND. Effects of plant-based diets on plasma lipids. Am J Cardiol. 2009;104(7):947-56.
Kadoch MA. The power of nutrition as medicine. Prev Med. 2012;55(1):80.
U.S. Food and Drug Administration. Major Food Sources of Trans Fat for American Adults (Average Daily Trans Fat Intake is 5.8 Grams or 2.6 Percent of Calories). .
Guasch-Ferre M, Babio N, Martinez-Gonzalez MA, Corella D, Ros E, Martin-Pelaez S, et al. Dietary fat intake and risk of cardiovascular disease and all-cause mortality in a population at high risk of cardiovascular disease. The American journal of clinical nutrition. 2015;102(6):1563-73.
Attur M, Krasnokutsky S, Statnikov A, Samuels J, Li Z, Friese O, et al. Low- grade inflammation in symptomatic knee osteoarthritis: prognostic value of inflammatory plasma lipids and peripheral blood leukocyte biomarkers. Arthritis Rheumatol. 2015;67(11):2905-15.
Berenbaum F. Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!). Osteoarthritis Cartilage. 2013;21(1):16-21.
Courties A, Gualillo O, Berenbaum F, Sellam J. Metabolic stress-induced joint inflammation and osteoarthritis. Osteoarthritis Cartilage. 2015;23(11):1955-65.
Edd SN, Giori NJ, Andriacchi TP. The role of inflammation in the initiation of osteoarthritis after meniscal damage. J Biomech. 2015;48(8):1420-6.
Rogers EL, Reynard LN, Loughlin J. The role of inflammation-related genes in osteoarthritis. Osteoarthritis Cartilage. 2015;23(11):1933-8.
Rahmati M, Mobasheri A, Mozafari M. Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges. Bone. 2016;85:81-90.
Dean E, Gormsen Hansen R. Prescribing optimal nutrition and physical activity as “first-line” interventions for best practice management of chronic low- grade inflammation associated with osteoarthritis: evidence synthesis. Arthritis. 2012;2012:560634.
Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes. 2007;56(4):1010-3.
de Luca K, Pollard H, Brantingham J, Globe G, Cassa T. Chiropractic management of the kinetic chain for the treatment of hip osteoarthritis: an Australian case series. J Manipulative Physiol Ther. 2010;33(6):474-9.
Thorman P, Dixner A, Sundberg T. Effects of chiropractic care on pain and function in patients with hip osteoarthritis waiting for arthroplasty: a clinical pilot trial. J Manipulative Physiol Ther. 2010;33(6):438-44.
Erridge C. The capacity of foodstuffs to induce innate immune activation of human monocytes in vitro is dependent on food content of stimulants of Toll- like receptors 2 and 4. The British journal of nutrition. 2011;105(1):15-23.
Gotsis E, Anagnostis P, Mariolis A, Vlachou A, Katsiki N, Karagiannis A. Health benefits of the Mediterranean Diet: an update of research over the last 5 years. Angiology. 2015;66(4):304-18.
Martinez-Gonzalez MA, Salas-Salvado J, Estruch R, Corella D, Fito M, Ros E, et al. Benefits of the Mediterranean Diet: Insights From the PREDIMED Study. Prog Cardiovasc Dis. 2015;58(1):50-60.
Barbaresko J, Koch M, Schulze MB, Nothlings U. Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review. Nutrition reviews. 2013;71(8):511-27.